Prevalence and Therapeutic Efficacy of Anthelmintic against Neoascaris vitulorum in Buffalo Populations from Sylhet District of Bangladesh

Background and Objectives: The epidemiological features of Neoascaris vitulorum infection in buffaloes are important to know their transmission risk factors assessment as well treatment regimens. This study was conducted with the objectives determining prevalence Sylhet district Bangladesh evaluate efficacy anthelmintics against parasite. Materials Method: A total 211 fecal samples were collected from examined for detection parasitic eggs during period July 2017 June 2018. For determination therapeutic efficacy, animals randomly divided into 6 groups (T0, Ti, T1, T2, T3, T4) where each group consisting 3 buffaloes. T0 (negative control-non infected) Ti (positive control-infected) treated only phosphate buffer saline (PBS). other four infected T1 albendazole, T2 piperazine citrate, T3 ivermectin T4 combination tetramisole HCL oxyclosanide. Before trials day 0 after 7th, 14th, 21st 28th days using McMaster technique. Results: overall estimated 17.06% (36/211). higher among buffalo calves below six months (39.28%) followed by 1 year, 2 years above 25%, 22.5% 7.20% respectively. rate high females (20.0%) than males (13.18%). parasite more prevalent rainy (21.42%) summer (16.67%) winter (14.29%) seasons. EPG results revealed citrate most effective (100%) vitulorum. percent efficacies anthelmintic used this oxyclozanide 95.49%, 86.20% 95.58% Conclusion: at relatively high. that highly reduction egg per gram (EPG) buffalo. On hand albendazole also around ninety